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Health Physics Society Journal

March 2011, Volume 100, Number 3

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  HP Cover and LWW advertisement image
On the cover: Victor P. Bond – See Guest Editorial by Musolino (p. 243) for more information.   LWW image

CONTENTS

SPECIAL ISSUE:

Proceedings of the Conference on Biological Consequences and Health Risks of Low-Level Exposure to Ionizing Radiation: In Honor of Victor P. Bond, Richland, Washington, 3-5 May 2010

EDITORIAL

The Enduring Legacy of Victor P. Bond — Stephen V. Musolino

INTRODUCTION — Ludwig E. Feinendegen, Antone L. Brooks, and William F. Morgan

PAPER

Biological Consequences and Health Risks of Low-Level Exposure to Ionizing Radiation: Commentary on the Workshop — Ludwig E. Feinendegen, Antone L. Brooks, and William F. Morgan

SESSION SUMMARIES AND ABSTRACTS

Senssion 1 Summary: Quantification of Low-Level Exposure and Primary Effects of Particle Tracks — Ludwig Feinendegen, Antone L. Brooks, and William F. Morgan

Abstracts

Quantification of Low-Level Exposure — L.A. Braby

Is a Dose Dose-Rate Effectiveness Factor (DDREF) Needed Following Exposure to Low Total Radiation Doses Delivered at Low Dose-Rates? — Antone L. Brooks

Exploring Biological Effects of Low Level Radiation from the Other Side of Background — Geoffrey Battle Smith, Yair Grof, Adrianne Navarrette, and Raymond A. Guilmette

Biological Consequences and Health Concerns from Low-Dose and Low-Dose-Rate Radiation in Mice and Humans — Taisei Nomura

SESSION 2: INTEGRATING PRIMARY AND SECONDARY EFFECTS USING SYSTEMS BIOLOGY

Session Summary 2a: Biological System Components — Ludwig E. Feinendegen, Antone L. Brooks, and William F. Morgan

Session Summary 2b: Responses in the System to Primary Effects — Ludwig E. Feinendegen, Antone L. Brooks, and William F. Morgan

Session Summary 2c: Secondary Reponses in the System—Non-Targeted Effects — Ludwig E. Feinendegen, Antone L. Brooks, and William F. Morgan

Abstracts

What Is the Use of Systems Biology Approaches in Radiation Biology? — Mary Helen Barcellos-Hoff

Systems-Related Facts and Consequences in Assessing Risk from Low-Level Irradiation — Ludwig E. Feinendegen, Ronald D. Neumann, and Myron Pollycove

Responses to Primary Effects: From Initial Events to Cellular Radiobiological Effects — Dietrich Averbeck

Interaction of Low Dose Radiation and Other Factors — Y. Shimada, M. Nishimura, Y. Amasaki, Y. Shang, K. Yamauchi, T. Sawai, S. Hirano, T. Imaoka, Y. Yamada, T. Takabatake, and S. Kakinuma

Radiation-Induced Genomic Instability — William F. Morgan

Individual Susceptibility to Radiosensitivity and to Genomic Instability: Its Impact on Low-Dose Phenomena — Adeline Granzotto, Clément Devic, Muriel Viau, Mira Maalouf, Aurélie Joubert, Catherine Massart, Charles Thomas, and Nicolas Foray

Stimulation of the Natural Anti-Tumor Cells by Single and Fractionated Irradiations of Mice with Low Doses of X-Rays — Ewa M. Nowosielska, Aneta Cheda, Jolanta Wrembel-Wargocka, and Marek K. Janiak

Health Effects from Low Dose Occupational and Medical Radiation Exposure and the Role of Adaptive Response — Nghi Phan and Douglas R. Boreham

SESSION 3: SPONTANEOUS AND RADIOGENIC EFFECTS: RISK AND PROGRESSION

The Impact of Adaptive and Non-Targeted Effects in the Biological Responses to Low Dose/Low Fluence Ionizing Radiation: The Modulating Effect of Linear Energy Transfer — Ludwig Feinendegen, Antone L. Brooks, and William F. Morgan

Session Summary 3b: Propagation of Effects and Low Dose Impact — Ludwig E. Feinendegen, Antone L. Brooks, and William F. Morgan

Abstracts

The Impact of Adaptive and Non-Targeted Effects in the Biological Responses to Low Dose/Low Fluence Ionizing Radiation: The Modulating Effect of Linear Energy Transfer — Sonia M. De Toledo, Manuela Buonanno, Min Li, Nesrin Asaad, Yong Qin, Geraldine Gonon, Grace Shim, Mariann Galdass, Yaa Boateng, Jie Zhang, and Edouard I. Azzam

Oxidative Stress-Induced Tumorigenesis in the Small Intestines of DNA Repair-Deficient Mice — Teruhisa Tsuzuki, Jing Shu Piao, Takuro Isoda, Kunihiko Sakumi, Yusaku Nakabeppu, and Yoshimichi Nakatsu

Metabolic Oxidative Stress and Low Dose Radiation Responses: Are Mitochondria Involved? — Douglas R. Spitz

A New Method of Assessing the Dose-Carcinogenic Effect Relationship in Patients Exposed to Ionizing Radiation: A Concise Presentation of Preliminary Data — Maurice Tubiana, Ibrahima Diallo, Sean Chavaudra, Dimitri Lefkopoulos, Jean Bourhis, Théodore Girinsky, André Brider, Mike Hawkins, Nadia Haddy, Chiraz El-Fayech, Elisabeth Adjadj, Enora Clero, and Florent de Vathaire

Neoplastic Transformation In Vitro: Is It a Valid Assay or Not for Assessing the Shape of the Dose-Response Curve for Radiation-Induced Cancer In Vivo? — J. Leslie Redpath

Radiation-Induced Non-Targeted Effects of Low Doses—What, Why and How? — Carmel Mothersill and Colin Seymour

SESSION 4: EPIDEMIOLOGY ON RADIATION-INDUCED CANCER

Session 4 Summary: Epidemiology of Radiation-Induced Cancer — Ludwig E. Feinendegen, Antone L. Brooks, and William F. Morgan

Abstracts

Dose Rate Dependence of Radiation Cancer Risk as Measured by Non-Tumor Dose — Hiroshi Tanooka

Implications of Radiation Epidemiologic Data for Risk Assessment and Radiation Protection — Roy E. Shore

Non-Radiation Causes of Carcinogenesis in the Atomic Bomb Survivors — Joseph M. Kaminski

SESSION 5: IMPLICATIONS ON PERCEPTION, MEDICINE, AND PROTECTION

Session 5 Summary: Implications on Perception, Medicine, and Protection — Ludwig E. Feinendegen, Antone L. Brooks, and William F. Morgan

Abstracts

Recommendations for Assessment of Consequences and Health Risks of Low-Level Exposure to Ionizing Radiation — Nicholas Dainiak

Patient Exposures and Consequent Risks from Nuclear Medicine Procedures — Roger W. Howell

Defending the Use of Medical Imaging — Cynthia H. McCullough

Low-Dose Radiotherapy of Disease — Myron Pollycove and Ludwig E. Feinendegen

Computed Tomography—Patient Dose and Dose Reduction Technologies — Stefan Ulzheimer, Heidrun Endt, and Thomas Flohr

Concepts to Reduce X-Ray Radiation in Interventional Radiology — Markus Lendl

SESSION 6: MODELING OF DOSE-RISK FUNCTIONS AND POLICY IMPLICATIONS

Session 6 Summary: Modeling of Dose-Risk Functions — Ludwig E. Feinendegen, Antone L. Brooks, and William F. Morgan

Abstracts

Science-Informed, Justified, and Optimized Radiation Safety Policies — Lawrence T. Dauer

Incorporating Information about Low-Level Exposure to Ionizing Radiation into Regulatory and Policy Decision-Making—Challenges and Opportunities — Paul A. Locke

Low-Dose-Radiation Activated Natural Protection and LNT — Bobby R. Scott

Hormetic Effects on Human Cancer Mortality Are Inducible Only after Long-Term Irradiation at Low Dose Rates — Sohei Kondo

SESSION 7: FINAL DISCUSSIONS, SUMMARY, RECOMMENDATIONS

Session 7 Summary: Final Discussions, Summary, and Recommendations — Ludwig E. Feinendegen, Antone L. Brooks, and William F. Morgan

Attendees

OTHER CONTENT

News and Notices

Health Physics Society Prospectus

Health Physics Society Affiliate Members

Author Guidelines

Advertisers Guide

Advertisers Index

Up and Coming

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Health Physics (ISSN 0017-9078) is the Official Journal of the Health Physics Society and is published monthly by Lippincott Williams and Wilkins, 351 West Camden Street, Baltimore, MD 21201-2436. For news and abstracts, and to search past issues of the Health Physics Journal, please visit the Health Physics Journal website.